RWE, HEOR & Evidence Synthesis
RWE, HEOR & Evidence Synthesis: Transforming patient care through evidence and insight
We believe every patient deserves the best care based on real-world evidence. By integrating data with human insight, we empower healthcare providers to make informed decisions that truly matter, driving better outcomes and value for everyone.
Axtria’s capabilities spans across product lifecycle covering real word evidence, economic modelling & evidence synthesis
Real World Evidence
- Integrated Evidence Planning
- Real World Data strategy, Primary medical data collection
- Causal inference studies
- End to end execution of RWE studies for regulatory approvals
- ML-based predictive analytics
- Synthetic control arm studies
- Digital twins
- Disease epidemiology & burden of illness
Health Economics & Outcomes Research
- Economic modeling (CEA, BIM, etc.)
- Patient simulation modeling
- Early & Launch Models
- Unmet value and gap analyses
- Model guides/Technical reports
- Country-specific models and dossiers
Evidence Synthesis
- Publication strategy
- Development – Abstract, manuscript, posters
- Systematic & Targeted literature reviews
- Global Value Dossiers
- AMCP Dossiers
- Meta-Analyses/Network Meta-Analyses/Matching Adjusted Indirect Comparison
Climb higher, see further: transcending limits with global talent
At Axtria, we help you climb the causal ladder—from simple observations to understanding true cause and effect. Our integrated approach bridges clinical trials and real-world practice, empowering you with deeper insights and more confident decisions across the product lifecycle.
Axtria's key differentiators and core values are to deliver the best research with the highest customer satisfaction
- Partnership
- Domain expertise
- Innovation
- Operating model
Partnership
01
PartnershipBy building strong partnerships, we become a trusted advisor to our clients. Our rich understanding of data ecosystems allows us to generate valuable insights from client data.
Domain expertise
02
Domain expertise50+ RWE/Data scientists, 200+ publications, and expertise in regulatory-grade evidence generation (simulations, analyses from descriptive to causal-inference methods, and Generative AI/ML/NLP)
Innovation
03
InnovationApproaches like causal inference, novel integrated data sources (e.g., SDoH), and AI-powered insights, automation, and patient facing chatbots
Operating model
04
Operating modelAdaptable engagement model (core and flex) and global SMEs/experts ready to meet evolving client requirements swiftly
Transformative evidence in action
Report
Anhedonia-Related Wording in Social Media: An Application of Natural Language Processing
Axtria used natural language processing techniques to analyze posts from mental health subreddits on Reddit to identify and classify mental disorders, particularly focusing on anhedonia, by applying machine learning algorithms to 9,887 posts from 2017 to 2022.
White Paper
Real-World Data-Based Simulations: Generating Medical Evidence From Clinical Trial And Real-World Data
Article
Modeling the "Difficult to Model" Disease: Considerations for Evaluating the Cost-Effectiveness in Rare Diseases
Report
Comparing Predictive Models: Traditional Versus Modern Statistical Approaches for Economic Outcomes in Major Depressive Disorder
Report
Burden of Illness of Intrauterine Adhesions Following Intrauterine Procedures: A Retrospective Analysis of Real-World Data
Report
A Cost-Effectiveness Analysis of Intrauterine Spacers Used to Prevent the Formation of Intrauterine Adhesions Following Endometrial Cavity Surgery
Recent publications
P37 Patients’ Perspectives on Muscular Dystrophy: Insights from Social Media Listening
Published in International Society for Pharmacoeconomics and Outcomes Research 2023
Event rates and risk factors for venous thromboembolism and major bleeding in a population of hospitalized adult patients with acute medical illness receiving enoxaparin thromboprophylaxis
Published in European Journal of Internal Medicine
OC 32.2 Risk of Venous Thromboembolism and Major Bleeding in Patients with Acute Medical Illness Receiving Thromboprophylaxis with Enoxaparin
Published in Research and Practice in Thrombosis and Haemostasis
Estimated impact of timely guidelines-based initiation of dual-combination anti-hypertensive therapy on long-term cardiovascular outcomes in a population of 1.4 million individuals
Published in European Heart Journal
Seeing the whole elephant: integrated advanced data analytics in support of RWE for the development and use of innovative pharmaceuticals
Published in Expert Review of Pharmacoeconomics & Outcomes Research
PB1487 - Venous Thromboembolism and Major Bleeding Risk in Hospitalized Obese Patients Receiving Thromboprophylaxis with Enoxaparin
Published in International Society on Thrombosis and Haemostasis 2023
A Real-World Evaluation of Primary Medication Nonadherence in Patients with Nonvalvular Atrial Fibrillation Prescribed Oral Anticoagulants in the United States
Published in American Journal of Cardiovascular Drugs
Clinical Benefits of Treating Patients with Type 2 Diabetes Mellitus with iGlarLixi: A Patient-Level Simulation Study
Published in Diabetes Therapy
Assessment of economic burden of fatigue in adults with multiple sclerosis: An analysis of US National Health and Wellness Survey data
Published in Multiple Sclerosis and Related Disorders
Event Rates and Risk Factors for Recurrent Cardiovascular Events and Mortality in a Contemporary Post Acute Coronary Syndrome Population Representing 239 234 Patients During 2005 to 2018 in the United States
Published in Journal of the American Heart Association
The Value of Oncology Therapies and Emerging Access Hurdles: Canada and the United States
Treatment pattern by hormone receptors and HER2 status in patients with metastatic breast cancer in the United Kingdom, Germany, France, Spain, and Italy (EU-5): Results from a physician survey
Published in American Society of Clinical Oncology
3504 POSTER Understanding the Variation in the Treatment Patterns for Newly Diagnosed Metastatic NSCLC Patient Among EU-5 Countries
Published in European Journal of Cancer
Client success stories
“A top 10 pharma company partnered with Axtria on a long-term COE model deploying a methodologist lead, onshore and offshore RWD programmers, data scientists, and a medical writer to support the enterprise RWE strategy. This team has helped accomplish label expansion, clinical guideline updates, and several publications with over 18 studies within 24 months.
In response to the specific requirements of a mid-tier pharma company, Axtria quickly deployed an expert team of SAS programmers and medical writers to fulfill the client's requests. Axtria’s insights helped the client identify important and necessary strategic shifts.”
Axtria research hub
Report